This statistic shows the total number of unique prescription medicines excluded from one or more formularies by the leading three U.S. pharmacy benefit managers (PBMs) in 2014-2022, by therapy area. Autonomic and central nervous system was the therapeutic class with the highest number of drugs excluded from one or more PBM formulary in the provided time interval.
Number of prescription medicines excluded from one or more pharmacy benefit manager (PBM) formulary in 2014-2022, by therapy area
Characteristic
Number of unique Rx drugs excluded
Autonomic and central nervous system
225
Diabetes, endocrine, metabolic, and weight loss
209
Dermatological
151
Oncology, hematological, and antineoplastic/immunosuppressant
117
Cardiovascular
109
Gastrointestinal
82
Musculoskeletal, rheumatology, and osteoarthritis
80
Respiratory
78
Obstetrical and gynecological
65
Ophthalmic
64
Antivirals and anti-infectives
61
Ear/nose/throat/mouth and allergies
32
Urological
28
020406080100120140160180200220240260
Add this content to your personal favorites. These can be accessed from the favorites menu in the main navigation.
You have no right to use this feature.
Make sure to contact us if you are interested in scientific citation.
You can upgrade your account to enable this functionality for all statistics.
This feature is not available with your current account.Request access
This statistic includes the leading three PBMs: CVS Caremark, Express Scripts, and Optum Rx. The total number — 1,357 — is higher than the 1,156 total for 2022 because some drugs were excluded and then added back to the formulary.
Learn more about how Statista can support your business.
AmerisourceBergen. (May 31, 2022). Number of prescription medicines excluded from one or more pharmacy benefit manager (PBM) formulary in 2014-2022, by therapy area [Graph]. In Statista. Retrieved June 05, 2025, from https://www.statista.com/statistics/1386462/pbm-formulary-exclusion-numbers-by-therapy-area/
AmerisourceBergen. "Number of prescription medicines excluded from one or more pharmacy benefit manager (PBM) formulary in 2014-2022, by therapy area." Chart. May 31, 2022. Statista. Accessed June 05, 2025. https://www.statista.com/statistics/1386462/pbm-formulary-exclusion-numbers-by-therapy-area/
AmerisourceBergen. (2022). Number of prescription medicines excluded from one or more pharmacy benefit manager (PBM) formulary in 2014-2022, by therapy area. Statista. Statista Inc.. Accessed: June 05, 2025. https://www.statista.com/statistics/1386462/pbm-formulary-exclusion-numbers-by-therapy-area/
AmerisourceBergen. "Number of Prescription Medicines Excluded from One or More Pharmacy Benefit Manager (Pbm) Formulary in 2014-2022, by Therapy Area." Statista, Statista Inc., 31 May 2022, https://www.statista.com/statistics/1386462/pbm-formulary-exclusion-numbers-by-therapy-area/
AmerisourceBergen, Number of prescription medicines excluded from one or more pharmacy benefit manager (PBM) formulary in 2014-2022, by therapy area Statista, https://www.statista.com/statistics/1386462/pbm-formulary-exclusion-numbers-by-therapy-area/ (last visited June 05, 2025)
Number of prescription medicines excluded from one or more pharmacy benefit manager (PBM) formulary in 2014-2022, by therapy area [Graph], AmerisourceBergen, May 31, 2022. [Online]. Available: https://www.statista.com/statistics/1386462/pbm-formulary-exclusion-numbers-by-therapy-area/
Profit from additional features with an Employee Account
Please create an employee account to be able to mark statistics as favorites.
Then you can access your favorite statistics via the star in the header.
Profit from the additional features of your individual account
Currently, you are using a shared account. To use individual functions (e.g., mark statistics as favourites, set
statistic alerts) please log in with your personal account.
If you are an admin, please authenticate by logging in again.
