Mean cost of U.S. hospitalizations with a brain/spine birth defect, 2019

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Jul 7, 2025

In 2019, it was estimated that the mean cost of hospitalizations with an encephalocele discharge diagnosis among those aged less than 65 years was around

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U.S. dollars. Spina bifida, anencephaly, and encephalocele are neural tube defects in which the neural tube does not close properly, often resulting in damage to the spinal cord and nerves. This statistic shows the mean cost of U.S. hospitalizations with a brain/spine birth defect–associated discharge diagnosis among those aged less than 65 years in 2019.

Mean cost of U.S. hospitalizations with a brain/spine birth defect–associated discharge diagnosis in 2019 (in U.S. dollars)

Characteristic	Mean cost in U.S. dollars
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Release date

July 2023

More information

Region

United States

Survey time period

2019

Age group

Younger than 65 years

Supplementary notes

The source notes that hospitalizations with at least one birth defect–associated discharge diagnosis were identified "by scanning up to 40 available fields for ICD-10-CM diagnosis codes Q00–Q99: congenital malformations, deformations, and chromosomal abnormalities. Patent ductus arteriosus (Q25.0) and atrial septal defect (Q21.1) were not considered birth defects when occurring in neonates aged <28 days or with an associated indicator of preterm birth (ICD-10-CM codes P07.2 or P07.3). An additional 23 conditions of lesser clinical importance classified within the Q00–Q99 code range were not considered birth defects."

Concerning birth defect categories the source notes: " Birth defects categories correspond to blocks of ICD-10-CM diagnosis codes: cardiovascular (Q20–Q28), central nervous system (Q00–Q07), chromosomal (Q90–Q99), cleft lip/palate (Q35–Q37), ear (Q16–Q17), eye (Q10–Q15), gastrointestinal (Q38–Q45), genitourinary (Q50–Q64), integumentary (Q80–Q85), musculoskeletal (Q65– Q79), and other syndrome (Q87). “Other defect” includes birth defects of the face and neck (Q18), respiratory system (Q30–Q34), and other congenital malformations (Q86 and Q89)."

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