As of 2023, some 28.4 percent of U.S. youths aged 12 to 17 years with a major depressive episode within the past year also used an illicit drug in the past year. This statistic depicts the percentage of youth in the United States with substance use as of 2023, sorted by major depressive episode.
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Substance use among youths in the United States as of 2023, by major depressive episode*
Characteristic
Had major depressive episode in the past year
Did not have major depressive episode in the past year
* Major depressive episode in the past year.
** Illicit Drugs include marijuana/hashish, cocaine (including crack), heroin, hallucinogens, inhalants, or prescription type
psychotherapeutics used non-medically.
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SAMHSA. (July 30, 2024). Substance use among youths in the United States as of 2023, by major depressive episode* [Graph]. In Statista. Retrieved July 27, 2025, from https://www.statista.com/statistics/252481/substance-use-among-us-youths-2011-by-major-depressive-episode/
SAMHSA. "Substance use among youths in the United States as of 2023, by major depressive episode*." Chart. July 30, 2024. Statista. Accessed July 27, 2025. https://www.statista.com/statistics/252481/substance-use-among-us-youths-2011-by-major-depressive-episode/
SAMHSA. (2024). Substance use among youths in the United States as of 2023, by major depressive episode*. Statista. Statista Inc.. Accessed: July 27, 2025. https://www.statista.com/statistics/252481/substance-use-among-us-youths-2011-by-major-depressive-episode/
SAMHSA. "Substance Use among Youths in The United States as of 2023, by Major Depressive Episode*." Statista, Statista Inc., 30 Jul 2024, https://www.statista.com/statistics/252481/substance-use-among-us-youths-2011-by-major-depressive-episode/
SAMHSA, Substance use among youths in the United States as of 2023, by major depressive episode* Statista, https://www.statista.com/statistics/252481/substance-use-among-us-youths-2011-by-major-depressive-episode/ (last visited July 27, 2025)
Substance use among youths in the United States as of 2023, by major depressive episode* [Graph], SAMHSA, July 30, 2024. [Online]. Available: https://www.statista.com/statistics/252481/substance-use-among-us-youths-2011-by-major-depressive-episode/
