This statistic shows a projection of the top 10 global pharmaceutical companies based on revenue generated by orphan drugs in 2030. For that year, it is projected that Roche's orphan drugs revenue will total **** billion U.S. dollars. Orphan drugs are used to target rare diseases or disorders, which in the United States is defined as less than ******* patients. The development of orphan drugs is currently incentivized in the United States through the Orphan Drug Act of 1983.
Products that have orphan and non-orphan drug
designations and are expected to generate less than 50% of their sales in 2024 from
their orphan-designated indication/s, are excluded from this statistic. This has led to the exclusion of therapies such as Avastin, Opdivo, Enbrel, Herceptin, Humira and Remicade.
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Evaluate. (March 14, 2025). Forecast of leading 10 pharmaceutical companies by global orphan drug revenue in 2030 (in billion U.S. dollars) [Graph]. In Statista. Retrieved July 11, 2025, from https://www.statista.com/statistics/373366/projected-top-10-companies-based-on-global-orphan-drug-revenue/
Evaluate. "Forecast of leading 10 pharmaceutical companies by global orphan drug revenue in 2030 (in billion U.S. dollars)." Chart. March 14, 2025. Statista. Accessed July 11, 2025. https://www.statista.com/statistics/373366/projected-top-10-companies-based-on-global-orphan-drug-revenue/
Evaluate. (2025). Forecast of leading 10 pharmaceutical companies by global orphan drug revenue in 2030 (in billion U.S. dollars). Statista. Statista Inc.. Accessed: July 11, 2025. https://www.statista.com/statistics/373366/projected-top-10-companies-based-on-global-orphan-drug-revenue/
Evaluate. "Forecast of Leading 10 Pharmaceutical Companies by Global Orphan Drug Revenue in 2030 (in Billion U.S. Dollars)." Statista, Statista Inc., 14 Mar 2025, https://www.statista.com/statistics/373366/projected-top-10-companies-based-on-global-orphan-drug-revenue/
Evaluate, Forecast of leading 10 pharmaceutical companies by global orphan drug revenue in 2030 (in billion U.S. dollars) Statista, https://www.statista.com/statistics/373366/projected-top-10-companies-based-on-global-orphan-drug-revenue/ (last visited July 11, 2025)
Forecast of leading 10 pharmaceutical companies by global orphan drug revenue in 2030 (in billion U.S. dollars) [Graph], Evaluate, March 14, 2025. [Online]. Available: https://www.statista.com/statistics/373366/projected-top-10-companies-based-on-global-orphan-drug-revenue/
