Atorvastatin was the top dispensed chemical drug in England in 2023 with more than 63 million items supplied. This drug is only available via a prescription in the United Kingdom and is used to lower the cholesterol of individuals who suffer from high cholesterol. Thus, reducing the risk of heart attacks and strokes in the process. The third most dispensed drug in this year was levothyroxine sodium which is used to treat those with an underactive thyroid gland, otherwise known as hypothyroidism.
The problem with cholesterol
High cholesterol is classed as having a cholesterol level in the blood supply higher than 5.0 mmol/l. High levels of cholesterol in England are particularly prevalent within people aged 55 and older. In 2018/19, there were approximately 76 percent of women aged 55 to 59 years were classed as living with high cholesterol. The amount of people living with excess levels of cholesterol in England can indicate a reason for Atorvastatin being the most dispensed drug in England.
Dangers of heart disease
As mentioned, another result of high cholesterol is the increased risk of heart disease. Although the number of people diagnosed with coronary heart disease has been fluctuating since 2012. In addition, the mortality rate from heart disease in the UK has been declining since 2000, accounting for 101 deaths per 100,000 population in 2021.
Leading chemical substances dispensed in England in 2023, by number of items
Characteristic
Number of items
Atorvastatin
63,715,915
Amlodipine
36,888,334
Omeprazole
35,725,773
Lansoprazole
34,336,696
Levothyroxine sodium
33,879,361
Ramipril
33,087,186
Bisoprolol fumarate
28,526,723
Colecalciferol
26,507,461
Metformin hydrochloride
25,163,549
Sertraline hydrochloride
23,069,827
Created with Highcharts 7.2.2Number of items63,715,91563,715,91536,888,33436,888,33435,725,77335,725,77334,336,69634,336,69633,879,36133,879,36133,087,18633,087,18628,526,72328,526,72326,507,46126,507,46125,163,54925,163,54923,069,82723,069,827AtorvastatinAmlodipineOmeprazoleLansoprazoleLevothyroxine sodiumRamiprilBisoprolol fumarateColecalciferolMetformin hydrochlorideSertraline hydrochloride
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Chemicals have been grouped and so may be used in more than one therapeutic area.
The number of prescription items dispensed. 'Items' is the number of times a product appears on a prescription form. Prescription forms include both paper prescriptions and electronic messages.
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NHSBSA. (June 6, 2024). Leading chemical substances dispensed in England in 2023, by number of items [Graph]. In Statista. Retrieved May 07, 2025, from https://www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/
NHSBSA. "Leading chemical substances dispensed in England in 2023, by number of items." Chart. June 6, 2024. Statista. Accessed May 07, 2025. https://www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/
NHSBSA. (2024). Leading chemical substances dispensed in England in 2023, by number of items. Statista. Statista Inc.. Accessed: May 07, 2025. https://www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/
NHSBSA. "Leading Chemical Substances Dispensed in England in 2023, by Number of Items." Statista, Statista Inc., 6 Jun 2024, https://www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/
NHSBSA, Leading chemical substances dispensed in England in 2023, by number of items Statista, https://www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/ (last visited May 07, 2025)
Leading chemical substances dispensed in England in 2023, by number of items [Graph], NHSBSA, June 6, 2024. [Online]. Available: https://www.statista.com/statistics/378445/prescription-cost-analysis-top-twenty-chemicals-by-items-in-england/
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