Number of prescription opioid overdose deaths U.S. 1999-2022

Published by
Preeti Vankar,
Jun 23, 2025

In 2022, there were an estimated ****** overdose deaths in the U.S. from prescription opioids, a significant increase from ***** deaths in 1999. This statistic presents the number of overdose deaths from prescription opioids in the U.S. from 1999 to 2022.

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Number of overdose deaths from prescription opioids in the U.S. from 1999 to 2022

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Release date

May 2024

Region

United States

Survey time period

1999 to 2022

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Topics

Opioid use in the U.S.Drug use in the U.S.The opioid epidemic in the U.S.Adolescent drug use in the U.S.Substance abuse treatment and rehabilitation in the U.S.
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