Death rates from opioid overdose in the U.S. in 2022, by state

Published by
Preeti Vankar,
Jun 23, 2025

In 2022, there were around ** deaths from opioid overdose per 100,000 population in the state of West Virginia, the highest rate of any U.S. state. This statistic shows the death rates from opioid overdose in the U.S. in 2022, by state, per 100,000 population.

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Opioid overdose death rates in the United States in 2022, by state (per 100,000 population)

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Sources

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Release date

August 2024

Region

United States

Survey time period

2022

Supplementary notes

Release date represents the date figures were accessed.

The source provides the following notes: 
"Age-adjusted death rates were calculated by applying age-specific death rates to the 2000 U.S. standard population age distribution.
Deaths from illegally-made fentanyl cannot be distinguished from pharmaceutical fentanyl in the data source. For this reason, deaths from both legally prescribed and illegally produced fentanyl are included in these data."

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Topics

Opioid use in the U.S.Drug use in the U.S.The opioid epidemic in the U.S.Adolescent drug use in the U.S.Substance abuse treatment and rehabilitation in the U.S.
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