In 2004, metformin was prescribed over 40 million times. In 2020 and 2021, the annual number of prescriptions had more than doubled and exceeded more than 90 million prescriptions. Metformin is primarily used for the treatment of type 2 diabetes. This statistic shows the total annual number of metformin hydrochloride prescriptions in the U.S. from 2004 to 2022, in millions.
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Number of metformin prescriptions in the U.S. from 2004 to 2022
(in millions)
Characteristic
Total prescriptions in millions
2004
40.89
2005
43.06
2006
54.45
2007
59.08
2008
69.8
2009
63.78
2010
68.69
2011
79.83
2012
76.94
2013
77.25
2014
86.13
2015
83.9
2016
81.31
020406080100120
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ClinCalc. (August 31, 2024). Number of metformin prescriptions in the U.S. from 2004 to 2022 (in millions) [Graph]. In Statista. Retrieved June 24, 2025, from https://www.statista.com/statistics/780332/metformin-hydrochloride-prescriptions-number-in-the-us/
ClinCalc. "Number of metformin prescriptions in the U.S. from 2004 to 2022 (in millions)." Chart. August 31, 2024. Statista. Accessed June 24, 2025. https://www.statista.com/statistics/780332/metformin-hydrochloride-prescriptions-number-in-the-us/
ClinCalc. (2024). Number of metformin prescriptions in the U.S. from 2004 to 2022 (in millions). Statista. Statista Inc.. Accessed: June 24, 2025. https://www.statista.com/statistics/780332/metformin-hydrochloride-prescriptions-number-in-the-us/
ClinCalc. "Number of Metformin Prescriptions in The U.S. from 2004 to 2022 (in Millions)." Statista, Statista Inc., 31 Aug 2024, https://www.statista.com/statistics/780332/metformin-hydrochloride-prescriptions-number-in-the-us/
ClinCalc, Number of metformin prescriptions in the U.S. from 2004 to 2022 (in millions) Statista, https://www.statista.com/statistics/780332/metformin-hydrochloride-prescriptions-number-in-the-us/ (last visited June 24, 2025)
Number of metformin prescriptions in the U.S. from 2004 to 2022 (in millions) [Graph], ClinCalc, August 31, 2024. [Online]. Available: https://www.statista.com/statistics/780332/metformin-hydrochloride-prescriptions-number-in-the-us/
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