Top pharma companies worldwide by number of originated drugs 2025

As of the beginning of 2025, U.S. company Pfizer had 166 originated drugs, making it the company with the highest number of originated drugs worldwide that year. 

Top pharma companies

In 2023, AbbVie was the pharmaceutical corporation that generated the highest revenue within the United States, namely some 42 billion U.S. dollars. Bristol-Myers Squibb and Johnson & Johnson stood in second and third, earning around 31 billion U.S. dollars, each.

Generics

Teva and Viatris are the top generic drug manufacturing companies in the United States in terms of unbranded generics' revenue. While the proportion of branded drugs versus generic drug prescriptions dispensed was much more balanced in 2005, around 89 percent of prescriptions were for unbranded generics in 2021. That year, only about eight percent of prescriptions were for brand-name drugs.