20 most abused prescription drugs in the U.S. by revenue 2016

Published by
Matej Mikulic,
Mar 23, 2021
This statistic shows the 20 most abused pharmaceutical drugs in the United States in 2016, sorted by revenue. According to the data, methlyphenidate HCl was the most abused pharmaceutical drug with 2016 sales reaching over two billion U.S. dollars.

Top 20 most abused prescription drugs in the U.S. in 2016, by revenue (in million U.S. dollars)

CharacteristicRevenue in million U.S. dollars
Methylphenidate HCl 2,073
OxyContin (oxycondone HCl controled-release) 1,390
Celecoxib 1,246
Buprenorphine and naloxone 1,026
Suboxone (buprenorphine and naloxone) 935
Concerta (methylphenidate HCl) 863
Celebrex (celecoxib capsule) 733
Fentanyl 560
Zolpidem tartrate 491
Celecox (celecoxib) 434.5
Adderall XR (amphetamine/dextroamphetamine) 363.8
Sertraline HCL 349
Hydromorphone HCl 316
Showing entries 1 to 13 (20 entries in total)
Created with Highcharts 7.2.2Revenue in million U.S. dollars2,0732,0731,3901,3901,2461,2461,0261,026935935863863733733560560491491434.5434.5363.8363.8349349316316304304304304288288288288282282242.3242.3132132Methylphenidate HClOxyContin (oxycondone HCl controled-release)CelecoxibBuprenorphine and naloxoneSuboxone (buprenorphine and naloxone)Concerta (methylphenidate HCl)Celebrex (celecoxib capsule)FentanylZolpidem tartrateCelecox (celecoxib)Adderall XR (amphetamine/dextroamphetamine)Sertraline HCLHydromorphone HClAmbien (zolpidem tartrate)Zoloft (sertraline HCl)Methylphenidate ERDuragesic (fentanyl transdermal system)Ritalin/Focalin (methylphenidate HCl)Subsys (fentanyl sublingual spray)Morphine suflate
02004006008001,0001,2001,4001,6001,8002,0002,2002,400

© Statista 2025
Download
Show detailed source information?
Register for free
Already a member?
Log in
Source

Use Ask Statista Research Service

Release date

September 2017

Region

United States

Survey time period

2016

Citation formats
Access all statistics starting from $2,388 USD yearly *

* For commercial use only

Basic Account

For single users
$0 USD
Always free
Register now
Access limited to Free Statistics. Premium Statistics are not included.
  • Free Statistics
Based on your interests

Starter Account

For single users
$199 USD
per month, billed annually 1
Buy now
  • Free Statistics
  • Premium Statistics

Professional Account

For teams of up to 5 people
$1,299 USD
per month, billed annually 1
Buy now
  • Free + Premium Statistics
  • Reports
  • Market Insights

1 All prices do not include sales tax. The account requires an annual contract and will renew after one year to the regular list price.

Compare accounts

Statistics on " Drug use in the U.S. "

Other statistics that may interest you Drug use in the U.S.

Prevalence of drug use in the U.S.

8

Teen drug use

8

Drug-related deaths

8

Treatment

4

Additional information

5

Further related statistics

10

Further Content: You might find this interesting as well

Statistics

Topics

Drug use in EuropeDrug use in the U.S.Adolescent drug use in the U.S.Drug use in CanadaSubstance addiction and drug use in Belgium
All features, all contents, at all times: Learn more about our professional solutions.

* For commercial use only

Basic Account

For single users
$0 USD
Always free
Register now
Access limited to Free Statistics. Premium Statistics are not included.
  • Free Statistics
Based on your interests

Starter Account

For single users
$199 USD
per month, billed annually 1
Buy now
  • Free Statistics
  • Premium Statistics

Professional Account

For teams of up to 5 people
$1,299 USD
per month, billed annually 1
Buy now
  • Free + Premium Statistics
  • Reports
  • Market Insights

1 All prices do not include sales tax. The account requires an annual contract and will renew after one year to the regular list price.

Compare accounts
Learn more about how Statista can support your business.