Number of e-prescriptions for controlled substances in the United States 2013-2024

Published by
Matej Mikulic,
Jun 13, 2025

This statistic depicts the total number of e-prescriptions for controlled substances (like opioids) in the United States, based on data of the country's largest e-prescribing operator Surescripts, from 2013 to 2024. In 2024, the total number of filed electronic prescriptions for controlled substances exceeded 310 million.

Number of e-prescriptions for controlled substances in the United States from 2013 to 2024 (in millions)

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Release date

2025

Region

United States

Survey time period

2013 to 2024

Supplementary notes

Statistic shows number of written e-prescriptions.
* For 2020, only number of filled prescriptions was available.

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